Circrnas: a regulator of cellular stress

Author: zorh

August undefined, 2024

WebFeb 8, 2024 · The brain is anatomically and functionally divided into distinct regions consisting of diverse cell types with complex transcriptome architectures [].Early studies have shown that circRNA expression is significantly different and highly enriched in the brains of wide range of mammals including mice, primates, and humans [10, 11].The … WebCircular RNAs (circRNAs) are a novel class of regulatory RNA involved in many biological, physiological and pathological processes by functioning as a molecular sponge, …

Frontiers Circular RNAs in the Regulation of Oxidative Stress

WebMar 2, 2024 · Recently, circRNAs have been extensively studied for their roles in cell signalling and regulation. This review aims to explain the structural as well as physiochemical properties of circular RNAs, looped … WebJan 17, 2024 · CircRNAs can be regulated by stress events such as at high and low temperatures, or under oxidative stress [6,11]. It has been reported that under stress, … flashboot 2.2 portable karanpc

Identification of circular RNAs expression pattern in caprine fetal ...

WebMicroRNAs (miRNAs) are linear single-stranded non-coding RNAs oligonucleotides, widely distributed in cells, playing a key role as regulators of gene expression at post … WebJul 27, 2024 · Studies have shown that the circRSU1-miR-93-5p-MAP3K8 axis plays a critical role in the regulation of circRSU1 in oxidative stress and ECM homeostasis in … WebAug 1, 2024 · The molecular function of circRNAs. (A)Acting as miRNA sponges. (B) Acting as protein coding function. CircRNAs are able to translated into proteins or peptides. (C) Acting as protein sponges. CircRNAs regulate the proteins function by interacting with RBPs. (D) Regulation of parental gene transcription. (a). flashboot 2.3 final portable karanpc

Circular RNAs in the Regulation of Oxidative Stress - PubMed

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WebJan 1, 2024 · Results: Genome-wide circRNA profiling by circRNA sequencing (circRNA-seq) revealed that a large number of circRNAs were induced by estrogen, and further … WebMay 27, 2024 · Circular RNAs (circRNAs) are a novel class of regulatory RNA involved in many biological, physiological and pathological processes by functioning as a molecular … flashboot 2.2 portableWebcircRNA ciRS-7 (circRNA sponge for miR-7), also known as Cdr1as, is a well-studied endogenous miRNA sponge that could associate with Argonaute 2 (Ago2) in a miR-7 … flashboot 2.3a

"WebSep 3, 2024 · In some situations, these databases are beneficial for research studying the functions and mechanisms of circRNAs; however, there is currently no database available that describes the transcriptional regulation of circRNAs, which limits researchers’ ability to easily obtain transcriptional regulation information about circRNAs, including TF ... " - Circrnas: a regulator of cellular stress

Circrnas: a regulator of cellular stress

WebFeb 10, 2024 · We cannot rule out that the DE lncRNAs/circRNAs identified under the cellular stresses tested have cell-type specificity. Although we have found a series of DE lncRNAs and circRNAs in cellular stress responses, investigations about functions of individual ncRNA of interest, and the molecular mechanism are required. WebJul 27, 2024 · Circular RNAs in the Regulation of Oxidative Stress Front Pharmacol. 2024 Jul 27;12:697903. doi: 10.3389/fphar.2024.697903. ... In this review, we described the relationship between oxidative stress and circRNAs, the circRNAs related to oxidative stress, and the role of circRNAs in promoting or inhibiting the occurrence and …

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WebCircular RNAs (circRNAs) are a novel class of noncoding RNAs that have been extensively explored in the past few years. The advent of new high-throughput sequencing … WebMar 10, 2024 · Epithelial-to-mesenchymal transition (EMT) is a dynamic program of cell plasticity aberrantly reactivated in cancer. The crosstalk between tumor cells and the …

WebAlthough the mechanism modulating circRNA levels during stress remains unclear, circRNAs are shown to be regulated during biogenesis, degradation, and exportation. …

WebApr 8, 2024 · Through the regulation of GBM cell proliferation, invasion, metastasis, angiogenesis, and apoptosis, certain circRNAs have been identified as tumor … WebApr 10, 2024 · Empty Cell: circRNAs Effect on endothelium; cZNF292: Regulates EC orientation and rearranges focal adhesion organisation under laminar flow: circHIPK3: ... Shear stress regulation of miR-93 and miR-484 maturation through nucleolin. Proc Natl Acad Sci U S A, 116 (26) (2024), pp. 12974-12979.

WebNov 10, 2024 · The ncRNAs, such as micro-RNAs (miRNAs), long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs), have been revealed to regulate cell growth and development in vitro and in vivo, further contributing to many hallmarks of disease phenotypes, including cancers.4, 5, 6 Mounting evidence has demonstrated that the …

WebAlthough the mechanism modulating circRNA levels during stress remains unclear, circRNAs are shown to be regulated during biogenesis, degradation, and exportation. As … flashboot 3.2 license keyWebJan 1, 2024 · CircRNAs can even be translated into proteins or peptides to perform biological functions [40]. 4. Regulation of tumor glucose metabolism by circRNAs. … flashboot alternativeWebSimilarly, some circRNAs also remain in the nucleus and are localized near the beginning of the transcription of their parental genes, possibly acting as positive regulators of Pol II … flash boost shimanoWebJun 26, 2024 · Circular RNAs (circRNAs), as a novel class of endogenously expressed non-coding RNAs (ncRNAs), have a high stability and often present tissue-specific … flash bootable cmdWebFeb 10, 2024 · We cannot rule out that the DE lncRNAs/circRNAs identified under the cellular stresses tested have cell-type specificity. Although we have found a series of … flash boot builder 2020WebSimilarly, some circRNAs also remain in the nucleus and are localized near the beginning of the transcription of their parental genes, possibly acting as positive regulators of Pol II and promoting the transcription of their parental genes (Figure 1B). Furthermore, circRNAs can act as scaffolds and link genes with transcription factor functions ... flash bootable software downloadWebJan 15, 2024 · Background/Aims: Circular RNAs (circRNAs), a type of RNA that is widely expressed in human cells, have essential roles in the development and progression of cancer. CircRNAs contain microRNA (miRNA) binding sites and can function as miRNA sponges to regulate gene expression by removing the inhibitory effect of an miRNA on its … flash boot builder