Determing c-myb protein level can isolate

Author: tcdx

August undefined, 2024

WebThe 48-kDa v-Myb protein is truncated relative to the normal 75-kDa c-Myb protein at both its amino and carboxyl termini (Figs. 1 and 2) (Gerondakis and Bishop, 1986; Rosson and Reddy, 1986). In addition, v-Myb contains 10 amino acid substitutions relative to the homologous region of c-Myb (a previously described eleventh substitution was not ... WebApr 7, 2024 · Watermelon (Citrullus lanatus) is an economically important cucurbit crop. Its pulp is rich in antioxidant carotenoids, which confer a variety of flesh colors. ClPsy1 (Phytoene Synthase) is the rate-limiting enzyme for carotenoid synthesis; however, the promoter activity of ClPsy1 is still unknown. In the present study, promoter sequences …

c-Myb is an essential downstream target for homeobox-mediated ...

WebThe transcription factor c-Myb was originally identified as a transforming oncoprotein encoded by two avian leukemia viruses. Subsequently, through the generation of mouse models that affect its expression, c-Myb has been shown to be a key regulator of hematopoiesis, including having critical roles in hematopoietic stem cells (HSCs). The … cycloplegics and mydriatics

MYB protein expression summary - The Human Protein Atlas

WebUsing this reporter line we demonstrate that subtypes of HSCs can be isolated based upon their respective c-Myb protein expression levels. HSCs expressing low levels of c-Myb … WebAug 1, 1991 · Various alterations of c-Myb itself may determine the lineage of differentiating hematopoietic cells, and the presence of either the normal amino or carboxyl terminus of c -Myb can suppress transformation when fused to v- myb. The protein product of the v-myb oncogene of avian myeloblastosis virus, v-Myb, differs from its normal cellular … WebDetermining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes. Hiroshi Sakamoto, Naoki Takeda, Fumio Arai, ... Proto-Oncogene Proteins c … cyclopithecus

MYB (Gene) - an overview ScienceDirect Topics

c-Myb Is an Evolutionary Conserved miR-150 Target and miR-150/c-Myb …

WebDetermining C-Myb Protein Levels can Isolate Functional Hematopoietic Stem Cell Subtypes. Sakamoto H, Takeda N, Arai F, Hosokawa K, Garcia P, Suda T, Frampton J, … WebJan 15, 2009 · It is well known that c-myb expression is highest in primitive hematopoietic cells and that down-regulation of its expression is an essential prerequisite for terminal differentiation. 15 It has been suggested that within this general framework, setting precise c-Myb levels is required for proper functioning during cell development. 16-20 The very … cyclopinclopanWebSep 21, 2010 · The dotted line indicates the position of the nonsense mutation that is predicted to cause truncation of the C-MYB protein in the medaka mutant. C-MYB. C-MYB was discovered as the cellular proto-oncogene from which the V-MYB oncogene arose via retroviral transduction in the avian myeloblastosis virus . This virus causes rapidly fatal ... cycloplegic eye refraction

"WebFeb 1, 2015 · The discrimination of HSC subpopulations based on c-Myb protein levels is not reflected in the levels of c-myb mRNA, there being no more than a 1.3-fold … " - Determing c-myb protein level can isolate

Determing c-myb protein level can isolate

Critical roles for c-Myb in hematopoietic progenitor cells.

WebAbstract The transcription factor c-Myb was originally identified as a transforming oncoprotein encoded by two avian leukemia viruses. Subsequently, through the generation of mouse models that affe... STEM CELLS, a peer reviewed journal published monthly, provides a forum for prompt publication of original investigative papers and concise ... WebThis protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] ...

Did you know?

WebAug 1, 2008 · TLDR. Analysis of c-myb gene transcriptional regulation using two cell lines modeling normal hematopoietic progenitor cells and transformed myelomonocytic blasts … WebOct 14, 2015 · miR-150 preferentially targets c-Myb protein levels in C2C12 myoblasts. ... Sakamoto, H. et al. Determining C-Myb Protein Levels can Isolate Functional …

WebThe 48-kDa v-Myb protein is truncated relative to the normal 75-kDa c-Myb protein at both its amino and carboxyl termini (Figs. 1 and 2) (Gerondakis and Bishop, 1986; Rosson … WebFeb 1, 2015 · The transcription factor c-Myb was originally identified as a transforming oncoprotein encoded by two avian leukemia viruses. Subsequently, through the generation of mouse models that affect its expression, c-Myb has been shown to be a key regulator of hematopoiesis, including having critical roles in hematopoietic stem cells (HSCs).

WebDec 2, 2009 · Determining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes. Sakamoto H, Takeda N, Arai F, Hosokawa K, Garcia P, Suda T, Frampton J, Ogawa M. Stem Cells, 33(2):479-490, 01 Feb 2015 Cited by: 4 articles PMID: 25329760 WebDetermining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes. Stem Cells. 2015; 33: 479-490. Crossref; PubMed; Scopus (7) Google Scholar). The correlations between G 0 M and these genes might not be detected because all these genes showed low RPKM (reads per kilobase of transcript per million mapped reads) …

WebAlthough c-Myb expression has been reported in the skin, colon, respiratory tract, retina, testes, primary fibroblasts, and endothelial cells, the protein is most readily detected in immature hematopoietic precursors at high levels. These levels of c-Myb decrease as cells progress toward terminal differentiation (17, 27, 54, 63). Alterations in ...

WebDetermining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes. Sakamoto H; Takeda N; Arai F; et al. See more; Stem Cells (2015) 33(2) 479-490. DOI: 10.1002/stem.1855. 7 Citations. Citations of this article. 30 Readers. Mendeley users who have this article in their library. cycloplegic mechanism of actionWebApr 10, 2024 · SNAREs (soluble N-ethylmaleimide-sensitive-factor attachment protein receptors) are engines for almost all of the membrane fusion and exocytosis events in organism cells. In this study, we identified 84 SNARE genes from banana (Musa acuminata). Gene expression analysis revealed that the expression of MaSNAREs varied a lot in … cyclophyllidean tapewormsWebUsing this reporter line we demonstrate that subtypes of HSCs can be isolated based upon their respective c-Myb protein expression levels. HSCs expressing low levels of c-Myb … cycloplegic refraction slideshareWebTISSUE-SPECIFIC STEM CELLS Determining c-Myb Protein Levels Can Isolate Functional Hematopoietic Stem Cell Subtypes HIROSHI SAKAMOTO,a NAOKI TAKEDA,b FUMIO ARAI,c KENTARO HOSOKAWA,c PALOMA GARCIA,d TOSHIO SUDA,c JON FRAMPTON,d MINETARO OGAWAa,e Key Words. Hematopoietic stem cells • Proto … cyclophyllum coprosmoidesWebDetermining c-Myb protein levels can isolate functional hematopoietic stem cell subtypes. Sakamoto H; Takeda N; Arai F; et al. See more; Stem Cells (2015) 33(2) 479 … cyclopiteWebJul 1, 2006 · Myb kd is a floxed-neo cassette inserted into intron 6 of the c-Myb gene. 37 This modification leads to a reduction of c-Myb protein expression to approximately 5% … cyclop junctionsWebIt is demonstrated that subtypes of HSCs can be isolated based upon their respective c‐Myb protein expression levels, and how essential it is to include protein studies when … cycloplegic mydriatics