WebJul 14, 2024 · Listen to our CEO, Dr Michael Hayden, talk about our phase 3 clinical trial PROOF-HD, in this video by @CheckRare Learn more about our study and #pridopidine … WebSep 17, 2024 · PROOF-HD is a global Phase 3, randomized, double-blind, placebo-controlled, parallel arm, multicenter study evaluating the efficacy and safety of …
PROOF-HD Study Enrolling Huntington Disease Patients
WebMar 28, 2024 · PROOF-HD is a Phase 3, randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of pridopidine (45 mg twice daily for 65 to 78 weeks), an oral, highly selective... Dr Michael Hayden is the founder and CEO of Prilenia Therapeutics, a clinical-stage biotech company focussed on developing novel treatments for neurodegenerative and neurodevelopmental disorders. He has authored approximately 900 peer-reviewed publications and is the most cited author for … See more “HD research presents several challenges,” says Hayden. “Firstly, as it is a slowly progressive neurodegenerative condition, it takes … See more There are currently a number of companies looking at gene therapy approaches. For instance, uniQure is focusing on decreasing huntingtin in the basal ganglia, with targeted delivery, which means … See more According to Hayden, the termination of these trials, which were focused on silencing the mutant Htt gene – known to drive the … See more Hayden is hopeful that the Phase III trial will confirm pridopidine’s therapeutic potential: “Pridopidine has an established safety and tolerability profile and potentially neuroprotective properties.” The drug candidate … See more chip bot download
Episode 22 - Dr. Michael Hayden and PROOF-HD - Apple
WebApr 30, 2024 · Michael Hayden, MBChB, PhD, CEO of Prilenia Therapeutics and a Killam Professor at the University of British Columbia, discusses the PROOF-HD trial. The … WebJul 8, 2024 · PROOF-HD is a Phase 3, randomized, double-blind, placebo-controlled study evaluating the effect of pridopidine on functional capacity in early-stage HD patients. It … chipbot gg